Neisseria meningitidis isolates can cause asymptomatic colonization or severe invasive infections. All isolates showed susceptibility to ceftriaxone, meropenem, ciprofloxacin, minocycline, and rifampin however, the susceptibility rates to penicillin and ampicillin for isolates with W and C capsules were 22% and 30%, respectively. In MLST analysis, 14 sequence types were found, and all isolates belonging to W showed the same molecular epidemiologic characteristics (W:P1.5-1, 2-2:F3-9:ST-8912).
W was no longer isolated after initiation of a vaccine programme for military trainees, but serogroup B caused meningitis in an army recruit training centre in 2015. There were five serogroup W isolates recovered from patients in military service. The most common serogroup was serogroup B (overall, 36%, n = 9/25 IMD, 37%, n = 7/19), which was isolated in every year of the research period except for 2011. Among isolates, 19 isolates were recovered from blood and/or cerebrospinal fluid (CSF) in 46 patients who suffered from invasive meningococcal disease (IMD), and six isolates were found in sputum or the throat. meningitidis isolates were collected in South Korea, in collaboration with the Korean Society of Clinical Microbiology. From April 2010 to November 2016, a total of 25 N.
Determination of the major serogroups is an important step for establishing a vaccine programme and management strategy targeting Neisseria meningitidis.
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